단백질칩 연구/분석 서비스

진온바이오텍 단백질칩 연구/분석 서비스

진온바이오텍의 단백질칩 연구/분석 서비스를 통해
로데이터(Raw data) 및 연구결과 보고서를 받아 보실 수 있습니다.

○ 로데이터(Raw data)

듀얼 스팟(Dual spot)으로 집적된 21,000개 이상의 단백질 전체의 로데이터(Raw data)

○ 데이터 분석(Data analysis)

(결과를 특정할 수 있는 부분(단백질명, 칩 상 위치) 제거)
데이터 분석을 통해 결과 도출 (강한 결합을 보이는 단백질 선정)

○ 결과 보고서

(결과를 특정할 수 있는 부분(단백질명, Uniprot 번호 등) 제거)
도출된 결과(강한 결합을 보이는 단백질)의 자세한 정보 제공

○ 보고서 목차

연구/분석 서비스 분야

단백질칩을 이용하여 샘플과 목적별로 다양한 연구/분석 서비스를 받아보실 수 있습니다.

○ 항체 테스트 : Antibody specificity / Cross-reactivity test

혈청 프로파일링 : Serum/Plasma profiling for Biomarker detection

단백질-단백질 결합 : Protein-Protein Interactions

소분자-단백질 결합 : Small molecule-protein Interactions

샘플만 준비하면 끝

샘플만 준비해주세요. 실험 전 과정은 저희가 맡겠습니다.

샘플 준비방법 :

○ 단백질/항체 :

100µg 이상의 정제된 단백질을 준비하여 보내주세요. 농도는 큰 상관 없으며, PBS버퍼 조건이 선호됩니다.
이후 냉동/냉장 포장 후 저희 연구실로 보내주세요.
A : 대전광역시 서구 둔산동 1392 봉화빌딩, B-101호

○ 기타 샘플 :

학술 상담을 요청하여 샘플 최적의 컨디션을 확인하세요.
T : 070-4124-9090
@ : gene@geneon.kr

빠른 연구결과 확인

샘플 전처리 완료 후 4주이내에 연구결과 보고서 및 로데이터(Raw data)를
받아서 확인하실 수 있습니다.
연구결과 보고서에는 Experiment details, Introduction, Protocol, Materials & Methods,
Sample optimization, 실험결과 개요, 스캐닝 이미지, 결과 분석, 결합단백질 정보,
Ontology analysis 등 연구 결과에 분석 전체 내용이 포함됩니다.

단백질칩, 단백질 칩, 바이오칩, 바이오 칩, 마이크로어레이, 마이크로 어레이, 프로틴 칩, 프로틴칩, Protein chip, Proteinchip, BioChip, Bio chip, 단백질 마이크로 어레이, DNA 마이크로 어레이, MicroArray, Micro Array, Protein microarray, protein micro array

Reference
Autoantibody Profiling

  • Fan W et al. (2019) Sa1679–Multiple rather than specific Antibodies were identified in Irritable Bowel Syndrome using Huprot™ Microarray Approach Gastroenterology 156 (6), Supplement 1, Page S-364
  • Lastwika KJ et al. (2019) Tumor-derived autoantibodies identify malignant pulmonary nodules. Am J Respir Crit Care Med, 199 (10)
  • Ye S et al. (2019) Plasma proteomic and autoantibody profiles reveal the proteomic characteristics involved in longevity families in Bama, China Clin Proteomics,16:22
  • Gowen MF et al. (2018) Baseline antibody profiles predict toxicity in melanoma patients treated with immune checkpoint inhibitors. J. Transl. Med., 16(1):82
  • Bigley V et al. (2018) Biallelic interferon regulatory factor 8 mutation: A complex immunodeficiency syndrome with dendritic cell deficiency, monocytopenia, and immune dysregulation. J. Allergy Clin Immunol, 141(6):2234-2248
  • Bremer HD et al. (2018) ILF2 and ILF3 are autoantigens in canine systemic autoimmune disease Sci.Rep. 8(1):4852
  • Chung JM et al. (2018) Identification of the thioredoxin-Like 2 Autoantibody as a Specific Biomarker for Triple-Negative Breast Cancer. J Breast Cancer 21:87-90
  • Pan J et al. (2017) Identification of Serological Biomarkers for Early Diagnosis of Lung Cancer Using a Protein Array-Based Approach. Mol Cell Proteomics 16 (12):2069-2078
  • Wang J et al. (2017) PTMA, a new identified autoantigen for oral submucous fibrosis, regulates oral submucous fibroblast proliferation and extracellular matrix. Oncotarget. 8(43): 74806–74819.
  • Gupta S et al. (2017) Serum Profiling for Identification of Autoantibody Signatures in Diseases Using Protein Microarrays. Methods Mol Biol 1619:303-315.
  • Gupta S et al. (2017) Evaluation of autoantibody signatures in meningioma patients using human proteome arrays. Oncotarget 8 (35): 58443-58456
  • Chung et al. (2017) Phenotyping and auto-antibody production by liver-infiltrating B cells in primary sclerosing cholangitis and primary biliary cholangitis J. Autoimmun 77:45-54
  • Ogishi et al. (2016) Delineation of autoantibody repertoire through differential proteogenomics in hepatitis C virus-induced cryoglobulinemia. Sci Rep 6:29532.
  • Yang L et al. (2016) Identification of serum biomarkers for gastric cancer diagnosis using a human proteome microarray. Mol Cell Proteomics 15(2):614-23.
  • Fiorentino DF et al. (2016) PUF60: a prominent new target of the autoimmune response in dermatomyositis and Sjögren’s syndrome. Ann Rheum Dis 75(6): 1145–1151.
  • Hu CJ et al. (2016) Identification of Novel Biomarkers for Behcet Disease Diagnosis Using HuProt Array Approach. Mol Cell Proteomics 16(2):147-156
  • Shi L et al. (2016) Application of high-throughput protein array in clinical screening for tumor markers. Int J Clin Exp Med 9:8529-8535.
  • Syed P et al. (2015) Autoantibody profiling of glioma serum samples to identify biomarkers using human proteome arrays Sci Rep 15(5):13895
  • Hu C et al. (2015) Autoantibody profiling on human proteome microarray for biomarker discovery in cerebrospinal fluid and sera of neuropsychiatric lupus. PLoS One 10(5):e0126643
  • Hu CJ et al. (2012) Identification of new autoantigens for primary biliary cirrhosis using human proteome microarrays. Mol Cell Proteomics 11(9):669-80.

Autoantibody Specificity and Crossreactivity

  • Venkataraman A et al. (2018) A toolbox of immunoprecipitation-grade monoclonal antibodies to human transcription factors. Nat Methods , in press
  • Ramos-López et al. (2018) Antibody Specificity Profiling using Protein Microarrays. In: Rockberg J., Nilvebrant J. (eds) Epitope Mapping Protocols, Methods in Molecular Biology, vol 1785. e0181251.
  • Washburn N et al. (2017) High-resolution physicochemical characterization of different intravenous immunoglobulin products. PLoS One 2017 Jul 31
  • Sterner E et al. (2017) Therapeutic Antibodies to Ganglioside GD2 Evolved from Highly Selective Germline Antibodies. Cell Rep 20(7):1681-1691
  • Kim YP et al (2014) Effective Therapeutic Approach for Head and Neck Cancer by an Engineered Minibody Targeting the EGFR Receptor. PLoS One. 1;9(12):e113442.
  • Liu S et al. (2014) Characterization of monoclonal antibody’s binding kinetics using oblique-incidence reflectivity difference approach. MAbs 7:110-119
  • Jeong JS et al. (2012) Rapid identification of monospecific monoclonal antibodies using a human proteome microarray. Mol Cell Proteomics 11(6):O111.016253