Epitope Mapping

What is EPITOPE MAPPING?

Epitope mapping refers to identifying the binding site (epitope) of an antibody to a target antigen.
Epitope mapping is an essential element in the development of monoclonal antibodies (mAb) for
diagnosis and treatment. It provides information on the specific amino acid sequence to which an antibody binds.

GENE ON BIOTECH provides the world’s best
Epitopemapping service based on
‘Antigen-Customized Peptidearray’.

EPITOPE MAPPING WITH 180,000 PEPTIDE ARRAY

GENE ON BIOTECH (180,000)0%
Company A (20,000)0%
Company P (5,000)0%

Gene On Biotech uses 180,000 peptides in one peptide array.
This provides more accurate and broader research results.
This is a distinguished feature in comparison to other companies that uses 5,500 – 20,000 peptides,

Our Epitope mapping service can provide distingushable data that can indentify information that may not be visible from other services.

In general, other peptide array shows implementation only on linear forms,
It was difficult to see the binding the antibodies on conformational epitopes.

However,

You can check antigens with discontinuous epitopes
because it shows tertiary structure as shown below.

Overview of EPITOPE MAPPING Research services

  • Confirming Sample-Peptide Interaction through peptide array experiment
  • Confirming Epitope by selection of top-ranked interactions based on intensity score
  • Confirming the 3D Structure/conformational form of the selected Epitope
  • (Optional) If an antigen is presented, perform sequence comparison between the antigen and the peptides confirmed by the experiment.

WORLD-BEST PEPTIDE ARRAY

Gene On Peptide Array: more than 180,000 peptides of more than 15-Amino acids
GENE ON BIOTECH provides world-class peptidearray research services.

Features and Benefits of

Epitope Mapping Service

1

Customized Antigen

It is difficult to clearly identify Epitopes with
random peptides. We manufacture customized
peptide arrays with sequences of target antigens.

2

All Cases Included

All the possible numbers of Peptide Epitopes that
an Antigen can have are included.
It includes linear form of numbers in all cases.

3

180,000 Spots

The manufactured Microarray contains all
mathematically possible Peptide Epitopes and
can be planted up to 180,000 spots.

Research/Analysis Services

You can receive raw data and research results.
Through GENE ON BIOTECH’s Epitope Mapping research analysis services.

step 1

Research Planning

  • Research Consulting and Academic Consultation
  • Confidentiality/Material Transfer Agreement
  • Setting Up the Entire Experiment Schedule

step 2

Peptide Synthesis & Manufacturing Microarray Manufacturing

  • Antigen Specific Peptides Calculation
  • Synthesis of Each Peptide After Confirmation
  • Peptides Microarray Manufacturing

step 3

Performing the Experiment

  • Sending and Receiving Samples
  • Sample Preprocessing and Condition Check
  • Perform Go Epitope Mapping

step 4

Sending Research Reports & Raw Data

  • Confirmation of Experiment Results and Data Mining
  • Write a Comprehensive Research Report
  • Sending Research Reports and Raw Data

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If you have any questions,

please contact us right now.

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